Liver Cancer Symptoms and Hepatocellular Carcinoma

Hepatocellular carcinoma often produces few or no symptoms in its early stages, especially in people who already have chronic liver disease. As a tumor grows, symptoms become more noticeable. Knowing the warning signs — and getting regular surveillance if you are at risk — can lead to earlier diagnosis and better outcomes.

Early Signs

Early liver cancer is frequently silent. When subtle symptoms appear, they may include unexplained fatigue, mild loss of appetite, or a vague discomfort in the upper-right abdomen.

Later Symptoms

• Unintended weight loss and loss of appetite
• Pain or a mass in the upper-right abdomen
• Abdominal swelling from fluid buildup (ascites)
• Jaundice — yellowing of the skin and the whites of the eyes
• Nausea, vomiting, and feeling full after eating only a small amount
• Weakness, fever, and itchy skin

When to Seek Care

Many of these symptoms can be caused by conditions other than cancer, but persistent or worsening signs should always be evaluated by a doctor. People with cirrhosis or chronic hepatitis should follow a regular liver cancer screening schedule even when they feel well, because surveillance can detect tumors before symptoms ever begin.

This page is for general education and is not medical advice. Contact a healthcare professional about any persistent symptoms.